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Summary Together, these findings demonstrate that elevated glucose results in actin polymerization that impedes both phases of biphasic insulin secretion, and that GLP-1 can restore glucose sensitivity and promote insulin release by correcting errors in actin dynamics at both phases

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Wilkinson said one of the strengths of the study is its duration, although he thinks additional studies are needed with an even longer follow-up

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Moreover, cinnamons effect on Ca 2+ channels in -cells may enhance first-phase insulin release

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